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e u r o p e a n u r o l o g y , vo l . 7 3 , n o . 1 , J a nu a ry 2 0 1 8

31

The “PROMIS” of Magnetic Resonance Imaging Cost Effectiveness in Prostate Cancer Diagnosis?

J. Walz

33

Improved Recovery of Erectile Function in Younger Men after Radical Prostatectomy: Does it Justify Immediate Surgery in Low-risk Patients?

J.K. Lee, D.D. Sjoberg, M.I. Miller, A.J. Vickers, J.P. Mulhall, B. Ehdaie

Active surveillance leads to better overall erectile function even where patients

are subject to delayed treatment.

38

Erectile Function Recovery After Surgery in Young Men with Low-risk Prostate Cancer: Probably Not Just a Matter of Age, Certainly Not the Main Point of Discussion

P. Capogrosso, F. Montorsi

40

Curative Treatment for Muscle Invasive Bladder Cancer in Elderly Patients: A Systematic Review

V. Fonteyne, P. Ost, J. Bellmunt, J.P. Droz, P. Mongiat-Artus, B. Inman, E. Paillaud, F. Saad,

G. Ploussard

Elderly patients with muscle invasive bladder cancer treated with curative treatment

have acceptable outcomes, although it worsens with age. Late morbidity

is comparable between older and younger patients. Studies evaluating the impact

of using geriatric assessments are needed.

51

Bladder Cancer in the Elderly

M. Babjuk

53

Intravenous Mannitol Versus Placebo During Partial Nephrectomy in Patients with Normal Kidney Function: A Double-blind, Clinically-integrated, Randomized Trial

M. Spaliviero, N.E. Power, K.S. Murray, D.D. Sjoberg, N.E. Benfante, M.L. Bernstein, J. Wren,

P. Russo, J.A. Coleman

Using intravenous mannitol intraoperatively to mitigate the effects of renal ischemia

during nephron-sparing surgery was not associated with improved renal function

outcomes in this prospective, randomized, placebo-controlled, double-blind trial;

the practice should be discontinued.

60

Should Urologists Abandon the Use of Mannitol During Partial Nephrectomy?

P.H. Shah, B.C. Leibovich, T.D. Lyon

62

Adjuvant Sunitinib for High-risk Renal Cell Carcinoma After Nephrectomy: Subgroup Analyses and Updated Overall Survival Results

R.J. Motzer, A. Ravaud, J.-J. Patard, H.S. Pandha, D.J. George, A. Patel, Y.-H. Chang, B. Escudier,

F. Donskov, A. Magheli, G. Carteni, B. Laguerre, P. Tomczak, J. Breza, P. Gerletti, M. Lechuga,

X. Lin, M. Casey, L. Serfass, A.J. Pantuck, M. Staehler

Further to the positive outcome in the overall S-TRAC population, most subgroups

defined by baseline characteristics demonstrated longer disease-free survival

on sunitinib versus placebo, including patients with a higher risk of recurrence than

the overall population, and patients with Fuhrman grade 3/4.

69

Are We Ready for Adjuvant Sunitinib in High-risk Renal Cell Carcinoma?

J. Casuscelli, J.J. Hsieh

71

Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling

S.K. Pal, S.M. Ali, E. Yakirevich, D.M. Geynisman, J.A. Karam, J.A. Elvin, G.M. Frampton, X. Huang,

D.I. Lin, M. Rosenzweig, D. Lipson, P.J. Stephens, J.S. Ross, V.A. Miller, N. Agarwal, B. Shuch,

T.K. Choueiri, J.H. Chung

Papillary renal cell carcinoma (PRCC) is a rare subtype of kidney cancer,

and understanding of the biology of advanced PRCC is limited. This report highlights

some of the unique biologic features of PRCC that may inform on future use

of targeted therapies for the treatment of metastatic disease.

Bladder Cancer

Kidney Cancer