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[3]

Prekovic S, van Royen ME, Voet AR, et al. The effect of F877L and T878A mutations on androgen receptor response to enzalutamide. Mol Cancer Ther 2016;15:1702 12

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[4]

Wyatt AW, Azad AA, Volik SV, et al. Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer. JAMA Oncol 2016;2:1598 606

.

[5]

Rijnders M, deWit R, Boormans JL, Lolkema MPJ, van der Veldt AAM. Systematic review of immune checkpoint inhibition in urological cancers. Eur Urol 2017;72:411 23

.

[6] Wang B, Lo UG, Wu K, et al. Developing new targeting strategy for

androgen receptor variants in castration resistant prostate cancer.

Int J Cancer. In press.

http://dx.doi.org/10.1002/ijc.30893 .

Marzia Del Re

a,

*

Elisa Biasco

b

Stefania Crucitta

a

Lisa Derosa

b,

y

Eleonora Ro

fi

a

Cinzia Orlandini

b

Mario Miccoli

c

Luca Galli

b

Alfredo Falcone

b

Guido W. Jenster

d

Ron H. van Schaik

e

Romano Danesi

a

a

Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical

and Experimental Medicine, University of Pisa, Pisa, Italy

b

Medical Oncology Unit, Department of Translational Research and New

Technologies in Medicine, University of Pisa, Pisa, Italy

c

Department of Clinical and Experimental Medicine, University of Pisa, Pisa,

Italy

d

Department of Urology, Erasmus University Medical Center, Rotterdam, The

Netherlands

e

Department of Clinical Chemistry, Erasmus University Medical Center,

Rotterdam, The Netherlands

*Corresponding author. Clinical Pharmacology and Pharmacogenetics

Unit, Department of Clinical and Experimental Medicine, University of

Pisa, 55 Via Roma, Pisa 56126. Italy. Tel. +39 050 2218646.

E-mail address:

marzia.delre@gmail.com

(M. Del Re).

y

Current af

fi

liation:

Medical Oncology, Institut Gustave Roussy, Villejuif, France.

July 26, 2017

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