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Conflicts of interest:

All authors declare no con

fl

icts of interest.

References

[1]

Sweeney CJ, Chen YH, Carducci M, et al. Chemohormonal therapy in metastatic hormone-sensitive prostate cancer. N Engl J Med 2015;373:737 46

.

[2]

James ND, Sydes MR, Clarke NW, et al. Addition of docetaxel, zoledronic acid, or both to fi rst-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet 2016;387:1163 77

.

[3]

Gravis G, Fizazi K, Joly F, et al. Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial. Lancet Oncol 2013;14:149 58

.

[4]

Fizazi K, Tran N,

[9_TD$DIFF]

Fein L, et al. Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer. N Engl J Med 2017;

[10_TD$DIFF]

377:352 60

.

[5]

James ND, de Bono JS, Spears MR, et al. Abiraterone for prostate cancer not previously treated with hormone therapy. N Engl J Med 2017;377:338 51

.

a

Academic Unit of Medical Oncology, Policlinico Hospital San Martino-IST,

Genoa, Italy

b

Department of Internal Medicine, School of Medicine, University of Genoa,

Genoa, Italy

c

Oncology Unit, Istituto Fondazione G. Giglio, Cefalu

, Italy

*Corresponding author. Academic Unit of Medical Oncology, Policlinico

Hospital San Martino-IST, Largo R. Benzi 10, 16132 Genoa, Italy;

Department of Internal Medicine, School of Medicine, University of

Genoa, Genoa, Italy. Fax: +39 010352753.

E-mail address:

carlo.messi@hotmail.it

(C. Messina

a

[5_TD$DIFF]

).

July 25, 2017

http://dx.doi.org/10.1016/j.eururo.2017.07.030

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