56 148
Table 1
–
Characteristics of participants
Statistic
Placebo (
N
= 98; 49%)
Mannitol (
N
= 101; 51%)
Age at surgery (yr)
Median (IQR)
56 (48, 63)
60 (50, 66)
Sex
Female
n
(%)
37 (38)
36 (36)
Male
n
(%)
61 (62)
65 (64)
Race
White
n
(%)
80 (82)
81 (80)
Black
n
(%)
10 (10)
5 (5.0)
Asian
n
(%)
5 (5.1)
5 (5.0)
Other
n
(%)
1 (1.0)
4 (4.0)
Unknown
n
(%)
2 (2.0)
6 (5.9)
Minimally invasive procedure
n
(%)
41 (42)
41 (41)
Clamping
n
(%)
97 (99)
100 (99)
Cold ischemia used
n
(%)
54 (56)
58 (59)
Clamp time cold ischemia (min)
Median (IQR)
27 (24, 35)
30 (23, 35)
Clamp time warm ischemia (min)
Median (IQR)
19 (16, 24)
20 (16, 25)
BMI
Median (IQR)
30 (27, 34)
30 (27, 34)
Baseline serum hemoglobin
Median (IQR)
13.7 (12.8, 14.7)
13.8 (12.9, 14.8)
Baseline serum albumin (
N
= 148)
Median (IQR)
4.4 (4.2, 4.6)
4.4 (4.3, 4.6)
ASA score
1
n
(%)
2 (2.0)
1 (1.0)
2
n
(%)
34 (35)
39 (39)
3
n
(%)
60 (61)
57 (56)
4
n
(%)
2 (2.0)
4 (4.0)
Karnofsky Scale at baseline
60
n
(%)
1 (1.0)
0 (0)
70
n
(%)
1 (1.0)
0 (0)
80
n
(%)
2 (2.0)
4 (4.0)
90
n
(%)
13 (13)
16 (16)
100
n
(%)
80 (82)
81 (80)
Unknown
n
(%)
1 (1.0)
0 (0)
Pathologic T stage
T0
n
(%)
8 (8.2)
9 (8.9)
T1
n
(%)
0 (0)
2 (2.0)
T1A
n
(%)
61 (62)
68 (67)
T1B
n
(%)
19 (19)
13 (13)
T2B
n
(%)
0 (0)
1 (1.0)
T3A
n
(%)
9 (9.2)
8 (7.9)
T3B
n
(%)
1 (1.0)
0 (0)
Histology
Angiomyolipoma
n
(%)
5 (5.1)
3 (3.0)
Chromophobe
n
(%)
7 (7.1)
10 (10)
Clear cell papillary
n
(%)
2 (2.0)
1 (1.0)
Conventional clear cell
n
(%)
58 (59)
56 (55)
Cystic lesions
n
(%)
0 (0)
2 (2.0)
Metanephric adenoma
n
(%)
0 (0)
1 (1.0)
Oncocytoma
n
(%)
7 (7.1)
6 (5.9)
Other
n
(%)
4 (4.1)
4 (4.0)
Papillary
n
(%)
15 (15)
18 (18)
Charlson Comorbidity Index
0
n
(%)
66 (67)
71 (70)
1
n
(%)
20 (20)
12 (12)
2
n
(%)
10 (10)
12 (12)
3
n
(%)
2 (2.0)
5 (5.0)
5
n
(%)
0 (0)
1 (1.0)
Intraoperative urine output, ml (
N
= 193)
Median (IQR)
175 (130, 250)
200 (120, 280)
Intraoperative IV
fl
uid intake, ml (
N
= 192)
Median (IQR)
2300 (1900, 2900)
2300 (2000, 2850)
RENAL Nephrometry Score
4
n
(%)
3 (3.1)
6 (5.9)
5
n
(%)
4 (4.1)
2 (2.0)
6
n
(%)
10 (10)
8 (7.9)
7
n
(%)
15 (15)
12 (12)
8
n
(%)
14 (14)
12 (12)
9
n
(%)
6 (6.1)
6 (5.9)
10
n
(%)
8 (8.2)
11 (11)
11
n
(%)
2 (2.0)
1 (1.0)
Unknown
n
(%)
36 (37)
43 (43)
Maximal tumor diameter, cm (
N
= 192)
Median (IQR)
3.0 (2.3, 4.0)
2.7 (1.9, 4.0)
Preoperative eGFR
Median (IQR)
89 (78, 100)
86 (71, 99)
Preoperative eGFR
<
60
n
(%)
5 (5.1%)
13 (13%)
Scan result preop for side of tumor (
N
= 195)
Median (IQR)
49 (47, 52)
50 (47, 53)
ASA = American Society of Anesthesiologists; BMI = body mass index; eGFR = estimated glomerular
fi
ltration rate; IQR = interquartile range; IV = intravenous;
preop = preoperative.
E U R O P E A N U R O L O GY 7 3 ( 2 0 18 ) 5 3
–
5 9
56