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Genentech/Roche, Novartis, Janssen, Astellas, Celldex, and Acerta; and

grants and consulting fees from Exelixis, P

fi

zer, Sano

fi

, Innocrin Pharma,

and BMS. Bernard Escudier has received consulting fees from Bayer,

P

fi

zer, and Novartis; and honoraria from Bayer, Roche, P

fi

zer, Genentech,

Novartis, and AVEO. Frede Donskov has received research funding from

P

fi

zer, Novartis, and GSK. Ahmed Magheli has received

fi

nancial

compensation for speeches from Janssen, Bayer, Astellas, and P

fi

zer.

Brigitte Laguerre has received honoraria from P

fi

zer. Michelle Casey,

Paola Gerletti, Mariajose Lechuga, Xun Lin, and Lucile Serfass are

employees of and own stock in P

fi

zer. Allan J. Pantuck has received

consulting fees from P

fi

zer. Michael Staehler has received honoraria,

consulting fees, and research grants from P

fi

zer, Bayer, GSK, Roche, BMS,

Novartis, Exelixis, and AVEO. Hardev S. Pandha has received honoraria for

advisory work from Ipsen and Esai. Piotr Tomczak, Giacomo Carteni,

Jan Breza, Anup Patel, and Yen-Hwa Chang have nothing to disclose.

Funding/Support and role of the sponsor:

These analyses were designed,

funded, and conducted by P

fi

zer. The S-TRAC study fromwhich data were

collected for these analyses was sponsored by P

fi

zer. Medical writing

support was provided by Vardit Dror of Engage Scienti

fi

c Solutions

and was funded by P

fi

zer Inc. The sponsor played a role in the design and

conduct of the study; data collection, management, and analysis;

and review and approval of the manuscript.

Acknowledgments:

Patients treated at the Memorial Sloan Kettering

Cancer Center were supported in part by a Memorial Sloan Kettering

Cancer Center Support Grant/Core Grant (P30 CA008748).

References

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