102 148
Table 6
–
Oncological outcomes of included patients with a history of prostate cancer: renal transplantation (I) versus renal replacement therapy (C)
Study (1st author, yr)
Primary
management
Arms
(no. of
patients)
Oncological outcomes
Histological
outcome and
prognosis (pTNM
and/or nomogram)
Follow-up
a(yr)
Free time to
transplantation
(yr)
Recommendations concerning waiting
period & prognostic factors of
recurrence, according to authors of the
included studies
Cancer recurrence
Cancer-speci
fi
c
survival
Overall survival
5 years
>
5 years
5 years
>
5 years
5 years
>
5 years
Tillou, 2014
[25]16 Prostatectomy
3 Prostatectomy +
adjuvant EBRT
I (14)
0%
NS
100%
NS
100%
NS
D
’
Amico:
Low risk 53%,
intermediate 43%
10-yr progression
without recurrence
MSKCC 97% (mean)
3.2
2.7
Waiting period among D
’
Amico
classi
fi
cation:
- 1 yr for low risk
- 2 yr for intermediate risk
- 5 yr for high risk
C (5)
0%
NS
100%
NS
100%
NS
Schonberger,
2002
[39]2 Prostatectomy
I (1)
0%
NS
100%
NS
100%
NS
pT2 R0
4.0
4
Prognostic factor of recurrence: stage T
Waiting period: at least 2 yr for organ
con
fi
ned disease
C (1)
0%
NS
100%
NS
100%
NS
Woodle, 2005
[9]55 Prostatectomy
13 Prostatectomy +
Adjuvant EBRT
12 Hormonotherapy
14 Radiotherapy
10 Unknown Rx
I (90)
NS
NS
96%
NS
62%
NS
Stage I 38%
Stage II 49%
Stage III 12%
3.3
1.6
Prognostic factor of recurrence:
- Stage
- Initial PSA
Waiting period:
- 2 yr for stage I/II or low Gleason
score
- 5 yr for stage III or high Gleason
score
Chahwan, 2017
[38]
35 Prostatectomy,
8 Prostatectomy +
adjuvant EBRT
(5 positive
margins, 3 pT3a)
4 EBRT
2 brachytherapy
I (52)
0%
4%
100%
NS
100%
NS
D
’
Amico:
Low risk 52%
Intermediate 46%
High 2%
3
2.1 for
D
’
Amico
low risk
3.6 for
D
’
Amico
intermediate/
high risk
Waiting period:
- 1 yr for D
’
Amico low risk
- 2 yr for D
’
Amico intermediate risk
- 5 yr for D
’
Amico high risk
Chapman, 2001
[46]
NS
I (5)
NS
20%
NS
NS
NS
NS
NS
NS
NS
-Prognostic factor of recurrence:
- Diagnosis of cancer while on
dialysis vs before dialysis
- Waiting period:
-
>
2 yr
-
>
5 yr if cancer diagnosed while on
dialysis
Kocak, 2009
[41]
1 Prostatectomy
(case report)
I (1)
NS
NS
100%
NS
100%
NS
D
’
Amico Low risk
Partin OC 84%,
EC15%, SV 1%, N0%
0.5
0.3
Waiting period:
- No waiting period for low-risk
cancer
- Consider Kattan nomogram
Ozcelik, 2015
[40]
1 Prostatectomy
(case report)
I (1)
0%
NS
100%
NS
100%
NS
D
’
Amico low risk
Partin OC 90%,
EP 5%, vs 1%,
N 1%
1.5
0.3
Waiting period:
- No waiting period for low-risk
cancer
Yiou, 1999
[26]
1 Prostatectomy
(case report)
I (1)
NS
NS
100%
NS
100%
NS
D
’
Amico high risk
pT2G7 (3 + 4) N0R0
4.5
4.0
C = control; EP = extraprostatic; I = intervention; N = node invasion; NS = not stated; OC = organ con
fi
ned; SV = seminal vesicle.
a
From cancer treatment to last news.
E U R O P E A N U R O L O GY 7 3 ( 2 0 18 ) 9 4
–
10 8
102