EURURO Vol. 73 No. 1

Evidence synthesis

3.1.

Quality of the studies

A total of 1891 studies were identified by the literature

search and two reviewers screened all study abstracts

independently. Of these, 53 studies were selected for full-

text screening and 20 studies were eligible for inclusion.

After an additional search in the references of these

20 studies and the elimination of duplicates with the

selection of the most up-to-date publication for each

series, 32 studies (4 retrospective comparative studies,

21 retrospective noncomparative studies, and 7 case

reports) were eligible for inclusion

( Fig. 1 )

. The quality

of studies was assessed as described above. RoB is

summarised in

Figure 2 .

Overall, there was a low RoB

across all studies. Study design was retrospective for all

studies.

3.2.

Characteristics of studies, population, and interventions

( Tables 1–4

)

In total, 2519 patients were included, suffering from: (1)

renal cell carcinoma (RCC;

= 1810, 72%), prostate cancer

(PC;

= 213, 8%), upper urinary tract carcinoma/bladder

cancer (UUTUC;

= 451, 18%), and testicular cancer (TC;

= 45, 2%). The time on dialysis before cancer treatment

ranged from 1 mo to 14 yr. Among these patients with a

history of urological cancer, 1733 (69%) remained on

dialysis, while 786 (31%) had a transplantation with a

waiting period ranging from 0 yr to

5 yr.

Tables 1 – 4

3.3.

Oncological outcomes

3.3.1.

Real cell carcinoma

Seventeen included studies evaluated patients suffering

from RCC

( Table 5 )

. Mean age at diagnosis ranged from 37 yr

[(Fig._2)TD$FIG]

Fig. 2

–

Evaluation of the risk of bias and confounders. (A) Bias and confounders for retrospective cohort studies. (B) Bias and confounders for case

reports. Blank domains stand for

“

not relevant

”

and concerns studies with no intervention (transplantation) arm.

E U R O P E A N U R O L O GY 7 3 ( 2 0 18 ) 9 4

–

10 8