EURURO Vol. 73 No. 1

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Table 5
–
Oncological outcomes of included patients with a history of renal carcinoma: renal transplantation (I) versus renal replacement therapy (C)
Study(1st author, yr)
No. of
nephrectomies
Arms (Nb)
Oncological outcomes
Histological outcomes
Follow-up
(yr)
Free time to
transplantation
(yr)
Recommendations concerning waiting
period & prognostic factors of
recurrence, according to authors of the
included studies
Cancer
recurrence
Cancerspeci
fi c
survival (time)
Overallsurvival(time)
Stage (%)
Grade (%)
Histologicsubtype (%)
5 yr
> 5 yr
Ryosaka, 2015
70 Solidtumours
I (17)
24% 41% 79% (
>
5 yr)
80% (
>
5 yr)
pT1 84%pT2
– 3 16%
Low 87%High 13%
CRCC 77%PRCC 17%Others 6%
3.8 3.6
2
- No waiting period if history of cystic
RCC
- Waiting period if history of solid RCC- Prognostic factors of recurrence:
- Tumour stage- Fuhrman grade
C (53)
0% 0% 100% (
>
5 yr)
83% (
>
5 yr)
132 Cystictumours
I (27)
0% 0% 100% (
>
5 yr)
100% (
>
5 yr)
pT1 93%pT2
– 3 7%
Low 92%High 8%
CRCC 76%PRCC 22%Others 2%
5.7 3.8
2
C (105)
2% 10% 96% (
>
5 yr)
80% (
>
5 yr)
Savaj, 2003
8
I (2)
NS NS 100% (1
– 5 yr)
100% (1
– 5 yr)
pT1 88%pT2 12%
NS
CRCC 63%PRCC 37%
10 7.4
4.3
C (6)
NS NS 100% (1
– 5 yr)
83% (1
– 5 yr)
Chapman, 2001
[46]
110
I (37)
NS 5.4% NS
NS
NS
NS
NS
5
NS
- Prognostic factor of recurrence:
- Diagnosis of cancer while on
dialysis vs before dialysis
- Waiting period:
-
> 2 yr
-
> 5 yr if cancer diagnosed while on
dialysis
C (73)
NS 18% NS
NS
Takagi, 2017
[30]
467
C (467)
NS NS 84% (5 yr)
76% (5 yr)
pT1
– 2 88%
pT3 5%pT4 6%
NS
CRCC 11%PRCC 77%Others 2%
4.8 4.7
NR
- Prognostic factors of cancer speci
fi c
survival:- Tumour stage- Fuhrman grade
Breda, 2015
58
I (58)
NS NS 95% (
>
5 yr)
NS
pT1 84%pT2-3 16%,N+ 1.7%M+ 1.7%
Low 77%High 23%
CRCC 79%PRCC 17%ChRCC 4%
7.5 (7
– 10)
NS
- Prognostic factors of cancer speci
fi c
survival:- Tumour size (HR 1.10)- Tumour stage (HR 1.46)- Node invasion (HR 2.22)- Visceral metastases (HR 3.49)- Fuhrman grade (HR 1.48)
Penn, 1997
[4]
71 Incidentaltumours
I (71)
1% NS 100% (1
– 5 yr)
NS
NS
NS
NS
5.75 (0
– 19)
1.1
- Waiting period:
- 5 yr for large (
>
5 cm) symptomatic
RCC
- 2 yr for small (
<
5 cm) symptomatic
RCC
- 0
– 2 yr for incidental RCC
- Prognostic factor of recurrence:
- Symptomatic vs incidental RCC- Tumour stage (size)
203Symptomatictumours
I (203)
27% NS 78% (1
– 5 yr)
NS
NS
NS
NS
3.83 (0
– 19)
Joshi, 2008
[29]
1
I (1)
NS NS 100% (
>
5 yr)
100% (
>
5 yr)
pT2b 100%
NS
NS
9
10
Sheashaa, 2011
12
I (12)
25% NS NS
95% (
>
5 yr)
pT1a 100%
Low 83%High 17%
CRCC 75%PRCC 17%ChRCC 8%
4.7
0
E U R O P E A N U R O L O GY 7 3 ( 2 0 18 ) 9 4 – 10 8 100